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Pharmacological Profiles of the Subtypes of Muscarinic Cholinoceptors That Mediate Aggregation of Pigment in the Melanophores of Two Species of Catfish

机译:Pharmacological Profiles of the Subtypes of Muscarinic Cholinoceptors That Mediate Aggregation of Pigment in the Melanophores of Two Species of Catfish

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Using selective antagonists, including pirenzepine, adiphenine, AF‐DX116, gallamine, and 4‐DAMP we attempted to characterize the muscarinic cholinoceptors on the melanophores of the translucent glass catfishKryptopterus bicirrhisand the mailed catfishCorydoras paleatus.The M3receptor‐selective antagonist, 4‐DAMP, potently inhibited the acetylcholine‐induced aggregation of pigment in both species. It appeared, therefore, that the receptors that mediated the cholinergically evoked aggregation of melanosomes in these species were of the M3muscarini

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