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Associations of increased physical performance and change in body composition with molecular pathways of heart disease and diabetes risk

机译:Associations of increased physical performance and change in body composition with molecular pathways of heart disease and diabetes risk

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摘要

Higher physical activity is associated with a reduced hazard for a plethora of diseases. It has remained unknown how the two primary physical activity-associated health effects, improved physical performance and change in body composition, independently modulate metabolic profiles toward a reduced risk for adverse outcomes. Here, we utilized a prospective cohort of 664 young men undergoing military service. We studied the metabolic associations of changes in muscle performance and body composition during military service (range 6-12 mo). We subsequently replicated our results for body composition change in 234 population-based samples with a 7-yr follow-up.

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