Ferritin-Polymer Conjugates: Grafting Chemistry and Integration into Nanoscale Assemblies

Yunxia Hu; Debasis Samanta; Sangram S .ParelkarSung Woo HongQian WangThomas P. RussellTodd Emrick

首页> 外文期刊>Advanced functional materials >Ferritin-Polymer Conjugates: Grafting Chemistry and Integration into Nanoscale Assemblies

【24h】

Ferritin-Polymer Conjugates: Grafting Chemistry and Integration into Nanoscale Assemblies

机译：Ferritin-Polymer Conjugates: Grafting Chemistry and Integration into Nanoscale Assemblies

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相关主题

摘要

Controlled free radical polymerization chemistry is used to graft polymer chains to the corona of horse spleen ferritin (HSF) nanocages. Specifically, poly(methacryloyloxyethyl phosphorylcholine) (poly M PC) and poly (PEC methacrylate) (polyPECMA) chains are grafted onto the nanocages by atom transfer radical polymerization (ATRP), in which the molecular weight of the polymer grafts is controlled by the monomer-to-initiator feed ratio. PolyM PC and poly PEG MA-grafted ferritin show a generally suppressed inclusion into diblock copolymer films relative to native ferritin, and the polymer coating is seen to mask the ferritin nanocages from antibody recognition. The solubility of poly PEC MA-coated ferritin in organic solvents enables its processing with polystyrene-fo/odr-poly(ethylene oxide) copolymers, and selective integration into the PEO domains of microphase-separated copolymer structures.

著录项

来源
《Advanced functional materials》 |2010年第20期|3603-3612|共10页
作者
Yunxia Hu; Debasis Samanta; Sangram S .ParelkarSung Woo HongQian WangThomas P. RussellTodd Emrick;
展开▼
作者单位

Department of Polymer Science and Engineering University of Massachusetts Amherst, MA 01003, USA;

Department of Chemistry and Biochemistry University of South Carolina Columbia, South, Carolina 29208, USA;

展开▼
收录信息
原文格式 PDF
正文语种英语
中图分类无线电电子学、电信技术;
关键词

Ferritin-Polymer Conjugates: Grafting Chemistry and Integration into Nanoscale Assemblies

摘要

著录项

相关主题

期刊订阅