Quality of life after hip, vertebral, and distal forearm fragility fractures measured using the EQ-5D-3L, EQ-VAS, and time-trade-off: results from the ICUROS

Axel Svedbom; Fredrik Borgstr?m; Emma HernlundOskar Str?mVidmantas AleknaMaria Luisa BianchiPatricia ClarkManuel Díaz CurielHans Peter DimaiMikk JürissonAnneli UuskülaMargus LemberRiina KallikormOlga LesnyakEugene McCloskeyOlga ErshovaKerrie M. SandersStuart SilvermanMarija TamulaitieneThierry ThomasAnna N. A. TostesonBengt J?nssonJohn A. Kanis

首页> 外文期刊>Quality of life research: An international journal of quality of life aspects of treatment, care and rehabilitation >Quality of life after hip, vertebral, and distal forearm fragility fractures measured using the EQ-5D-3L, EQ-VAS, and time-trade-off: results from the ICUROS

【24h】

Quality of life after hip, vertebral, and distal forearm fragility fractures measured using the EQ-5D-3L, EQ-VAS, and time-trade-off: results from the ICUROS

机译：Quality of life after hip, vertebral, and distal forearm fragility fractures measured using the EQ-5D-3L, EQ-VAS, and time-trade-off: results from the ICUROS

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相关主题

摘要

Abstract Introduction The International Costs and Utilities Related to Osteoporotic fractures Study is a multinational observational study set up to describe the costs and quality of life (QoL) consequences of fragility fracture. This paper aims to estimate and compare QoL after hip, vertebral, and distal forearm fracture using time-trade-off (TTO), the EuroQol (EQ) Visual Analogue Scale (EQ-VAS), and the EQ-5D-3L valued using the hypothetical UK value set. Methods Data were collected at four time-points for five QoL point estimates: within 2?weeks after fracture (including pre-fracture recall), and at 4, 12, and 18?months after fracture. Health state utility values (HSUVs) were derived for each fracture type and time-point using the three approaches (TTO, EQ-VAS, EQ-5D-3L). HSUV were used to estimate accumulated QoL loss and QoL multipliers. Results In total, 1410 patients (505 with hip, 316 with vertebral, and 589 with distal forearm fracture) were eligible for analysis. Across all time-points for the three fracture types, TTO provided the highest HSUVs, whereas EQ-5D-3L consistently provided the lowest HSUVs directly after fracture. Except for 13–18?months after distal forearm fracture, EQ-5D-3L generated lower QoL multipliers than the other two methods, whereas no equally clear pattern was observed between EQ-VAS and TTO. On average, the most marked differences between the three approaches were observed immediately after the fracture. Conclusions The approach to derive QoL markedly influences the estimated QoL impact of fracture. Therefore the choice of approach may be important for the outcome and interpretation of cost-effectiveness analysis of fracture prevention.

著录项

来源
《Quality of life research: An international journal of quality of life aspects of treatment, care and rehabilitation》 |2018年第3期|707-716|共10页
作者
Axel Svedbom; Fredrik Borgstr?m; Emma HernlundOskar Str?mVidmantas AleknaMaria Luisa BianchiPatricia ClarkManuel Díaz CurielHans Peter DimaiMikk JürissonAnneli UuskülaMargus LemberRiina KallikormOlga LesnyakEugene McCloskeyOlga ErshovaKerrie M. SandersStuart SilvermanMarija TamulaitieneThierry ThomasAnna N. A. TostesonBengt J?nssonJohn A. Kanis;
展开▼
作者单位

The Dartmouth Institute for Health Policy and Clinical Practice, Geisel School of Medicine at;

Stockholm School of Economics;

Institute for Health and Ageing, Australian Catholic UniversityMapiLIME/MMC, Karolinska InstitutetFaculty of Medicine, Vilnius UniversityBone Metabolism Unit, Istituto Auxologico Italiano IRCCSClinical Epidemiology Unit, Hospital Infantil Federico Gómez and Faculty of Medicine UNAMServicio de Medicina Interna/Enfermedades Metabolicas Oseas, Fundacion Jimenez DiazDivision of Endocrinology and Diabetology, Department of Internal Medicine, Medical University ofFaculty of Medicine, University of TartuUral State Medical UniversityAcademic Unit of Bone Metabolism, Centre for Integrated research in Musculoskeletal AgeingYaroslavl State Medical UniversityCedars-Sinai Medical Center and David Geffen School of Medicine, University of CaliforniaINSERM U1059, Lab Biologie Intégrée du Tissu Osseux, Service de Rhumatologie, CHU de Saint-Etienne;

展开▼
收录信息
原文格式 PDF
正文语种英语
中图分类医药、卫生;
关键词
Osteoporosis; Fracture; Health-related quality of life; Health utility;

Quality of life after hip, vertebral, and distal forearm fragility fractures measured using the EQ-5D-3L, EQ-VAS, and time-trade-off: results from the ICUROS

摘要

著录项

相关主题

期刊订阅