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首页> 外文期刊>Pesticide science >Action of the fungicide tridemorph on the glucose, lactate and succinate dehydrogenase activities of some tridemorph‐sensitive and ‐resistant bacteria
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Action of the fungicide tridemorph on the glucose, lactate and succinate dehydrogenase activities of some tridemorph‐sensitive and ‐resistant bacteria

机译：Action of the fungicide tridemorph on the glucose, lactate and succinate dehydrogenase activities of some tridemorph‐sensitive and ‐resistant bacteria

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AbstractThe systemic morpholine fungicide tridemorph, which is known to exert its antifungal action through inhibition of ergosterol biosynthesis, can also inhibit the growth of organisms which are incapable of sterol biosynthesis. It was found to inhibit strongly glucose and lactate dehydrogenase activities in cultures of four Gram( +) bacteria, Rhodococcus sp. AK 1, Bacillus cereus FranklandFrankland,Bacillus subtilis(Ehrenberg) Cohn,Nocardia asteroidesand a Gram(−) bacterium,Rhizobium leguminosarum.Growth of these bacteria was inhibited by tridemorph at concentrations between 7 and 60 mg litre−1. In contrast, similar dehydrogenase activities in other Gram(−) organisms,Escherichia coliCast.Chalm. andAzotobacter vinelandii, which showed no growth inhibition at 200 mg litre−1tridemorph, were either not inhibited or inhibited only slightly. Similarly, succinate dehydrogenase activity inRhodococcussp. AK 1 was more strongly inhibited by tridemorph than that in E.coli.In cell‐free extracts ofRhodococcussp. AK1 and E.coli, lactate dehydrogenase activity was also inhibited by tridemorph to a much greater extent in the sensitive strain (63) than in the resistant

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