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>The use of 3H permethrin to investigate the mechanisms underlying its differential toxicity to adult and larval stages of the sheen blowflyLucilia sericata
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The use of 3H permethrin to investigate the mechanisms underlying its differential toxicity to adult and larval stages of the sheen blowflyLucilia sericata
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机译：The use of 3H permethrin to investigate the mechanisms underlying its differential toxicity to adult and larval stages of the sheen blowflyLucilia sericata
AbstractObservations suggest that more than one mechanism is responsible for the increased tolerance to permethrin in the larval stage ofLucilia sericata.While the penetration rate of permethrin was much reduced in larvae, they remained more tolerant than adults when this compound was injected. Following the injection of sublethal amounts of 3H‐(1RS)‐trans‐permethrin, a substantial proportion of the dose was accumulated and retained in the larval fat body. In adults, less permethrin was absorbed and retained in the tissues. However, compared to the larvae, detoxication was faster, haemoplasm levels were lower, and substantially more breakdown products were excreted. The injection of sublethal amounts of permethrin into the larva led to severe disruption of sensory function. These findings suggest that an important difference may exist between adults and larvae in either the sensitivity of vital sites within the nervous system, or in the sequence of events which follow nervous system disruption and lead to
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