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>Effectiveness of Push/Pull Hemodiafiltration Using Large‐Pore Membrane for Shoulder Joint Pain in Long‐Term Dialysis Patients
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Effectiveness of Push/Pull Hemodiafiltration Using Large‐Pore Membrane for Shoulder Joint Pain in Long‐Term Dialysis Patients
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机译：Effectiveness of Push/Pull Hemodiafiltration Using Large‐Pore Membrane for Shoulder Joint Pain in Long‐Term Dialysis Patients
Abstract:Long‐term hemodialysis (HD) patients complaining of shoulder joint pain were treated by HD and by push/pull HDF using high‐flux synthetic membranes with large pores (Asahi PAN 20CX2) for 2 weeks. The results showed no significant difference in Kt/Vureabetween HD and push/pull HDF. Nevertheless, reduction of the plasma β2‐microglobulin was greater during push/pull HDF than during‐HD. These findings can be explained by far more convective flux in push/pull HDF than in HD: nearly 30 L during push/pull HDF vs. 3 L during HD. In the present study, there was no alleviation of the shoulder joint pain during HD treatment, whereas marked relief of the symptom was found during push/pull HDF treatment. Since the two treatment modalities differ simply in their efficiency in removing larger molecular weight substances, the joint pain alleviation effected by push/pull HDF could well be ascribed to elimination of an unknown larger molecular weight substance causing this symptom. However, a considerable amount of β2‐microglobulin was removed both by HD and push/pull HDF. Therefore, the substance causing the joint pain might be larger than β2
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