Licorice flavonold oil reduces oxldative stress and total body fat In overweight subjects:a randomized, double-blind, placebo-controlled study

Hiroshi Maruoka; Kaku Nakagawa; Junko MiyagiMasaaki Matsubara

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Licorice flavonold oil reduces oxldative stress and total body fat In overweight subjects:a randomized, double-blind, placebo-controlled study

机译：Licorice flavonold oil reduces oxldative stress and total body fat In overweight subjects:a randomized, double-blind, placebo-controlled study

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In this study with 30 nurses as study subjects, we examined how 12 weeks of a study treatment affected body measurements, blood biochemistry, and the oxidative stress regulatory system. Subjects were randomly divided into two groups: one that received licorice flavonoid oil (LFO) capsules and L-carnitine capsules (supplement group n = 15), and another that received placebo capsules (placebo group n = 15), for 12 consecutive weeks. Measurements of oxidative stresses and other tests were performed at baseline and after 4, 8, and 12 weeks of treatment. Results showed that only the supplement group showed a significant decrease in waist circumference at 8 weeks when compared to baseline, while neither group showed a change in body mass index. No changes in blood biochemistry were observed in either group. Only the supplement group showed a significant decrease in oxidative stresses at 8 weeks when compared to baseline, while the placebo group did not show any change. Both groups showed a significant decrease in anti-oxidant potential, but at 12 weeks the supplement group showed a significantly higher level than the placebo group. While the supplement group showed a stable BAP to d-ROM ratio (representing latent anti-oxidant potential), the placebo group had a significant decrease. These results demonstrate that 12 weeks of LFO and L-carnitine consumption decreases waist circumference and oxidative stresses and maintains latent anti-oxidant potential.

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来源
《Mediterranean journal of nutrition and metabolism》 |2013年第3期|239-246|共8页
作者
Hiroshi Maruoka; Kaku Nakagawa; Junko MiyagiMasaaki Matsubara;
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作者单位

School of Health and Social Services, Saitama Prefectural University, 820, Sannomiya, Koshigaya;

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原文格式 PDF
正文语种英语
中图分类生理学;
关键词
Licorice flavonoid oil; L-carnitine; Oxidative stress regulatory system; Total body fat;

Licorice flavonold oil reduces oxldative stress and total body fat In overweight subjects:a randomized, double-blind, placebo-controlled study

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