With the global trend in paediatric anaesthesia toward ambulatory surgery, the development of new inhalational anaesthetics that facilitate a rapid and complete emergence is essential. Sevoflurane and desflurane address this new trend. Sevoflurane is tolerated well when administered by mask whereas desflurane irritates the airway. Both drugs are excellent maintenance agents and facilitate a rapid recovery. Nevertheless, both drugs have disadvantages that require our careful consideration as we begin to explore their possible roles in paediatric anaesthesia.
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