Nuclear magnetic resonance-based metabolomics of OCT-embedded frozen kidney samples in mouse and man following standardized pre-analytics

Leenders Justine; Buemi Antoine; Mourad Michelde Tullio PascalJouret Francois

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Nuclear magnetic resonance-based metabolomics of OCT-embedded frozen kidney samples in mouse and man following standardized pre-analytics

机译：Nuclear magnetic resonance-based metabolomics of OCT-embedded frozen kidney samples in mouse and man following standardized pre-analytics

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Introduction Pre-analytical processing significantly affects tissue metabolomes. Since most frozen kidney samples are stored after embedding, standardization of cryoprotective medium removal before metabolomics is essential. Objectives We used rodent and human kidney samples to develop an easy and robust pre-analytical procedure compatible with H-1-nuclear magnetic resonance (NMR)-based metabolomics.

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来源
《Metabolomics :》 |2017年第8期|Article:94-Article:94|共8页
作者
Leenders Justine; Buemi Antoine; Mourad Michelde Tullio PascalJouret Francois;
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作者单位

Univ Liege, CIRM, Liege, Belgium;

Catholic Univ Louvain, St Luc Univ Hosp, Div Surg & Abdominal Transplantat, Brussels, Belgium;

Univ Liege Hosp ULg CHU, Div Nephrol, Liege, Belgium;

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原文格式 PDF
正文语种英语
中图分类生理学;
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Metabolomics; NMR; OCT; Kidney; Ischemia/reperfusion; Transplantation;

Nuclear magnetic resonance-based metabolomics of OCT-embedded frozen kidney samples in mouse and man following standardized pre-analytics

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