A feasibility study of working memory training for individuals with paediatric-onset multiple sclerosis

Till Christine; Kuni Bravina; De Somma EliseaYeh E. AnnBanwell Brenda

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A feasibility study of working memory training for individuals with paediatric-onset multiple sclerosis

机译：A feasibility study of working memory training for individuals with paediatric-onset multiple sclerosis

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Objective: To investigate the feasibility and experiences of paediatric-onset multiple sclerosis (MS) patients completing a working memory training programme. Methods: Nine paediatric-onset MS patients (mean age 19.3 +/- 4.1 years) identified as having attention and/or working memory difficulties underwent a five-week (five days/week) internet-based working memory training programme (Cogmed (TM)); weekly coaching was provided. Measures of adherence and tolerance were used to establish the feasibility of implementing computerised cognitive training. Qualitative experiences reported by the patients were analysed and factors that may modulate the effects of training were explored. Results: Six of the nine enrolled patients completed the programme within the recommended time, and all individuals, with the exception of one, were considered to tolerate the training well. Eight of the nine participants acknowledged that training was helpful in one or more ways. All but one participant reported improvements in working memory, although evidence for improvement on objective neuropsychological testing was limited. Lower normalised brain volume emerged as a potentially important variable in predicting extent of improvement on the training programme. Conclusion: Selected paediatric-onset MS patients can tolerate and complete an intensive cognitive rehabilitation programme. Future investigation of moderators of training effects and the stability of the findings over time is needed.

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《Neuropsychological rehabilitation》 |2019年第8期|1177-1192|共16页
作者
Till Christine; Kuni Bravina; De Somma EliseaYeh E. AnnBanwell Brenda;
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作者单位

York Univ, Dept Psychol, 4700 Keele St, Toronto, ON M3J 1P3, Canada;

Hosp Sick Children, Res Inst, Neurosci & Mental Hlth Program, Toronto, ON, Canada;

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正文语种英语
中图分类神经病学与精神病学;
关键词
Working memory training; multiple sclerosis; paediatric-onset; cognitive rehabilitation; feasibility;

A feasibility study of working memory training for individuals with paediatric-onset multiple sclerosis

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