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>Quantitative structure—activity relationships of light‐dependent herbicidal 4‐pyridone‐3‐carboxanilide derivatives II. Substituent effects of anilide and pyridone moieties
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Quantitative structure—activity relationships of light‐dependent herbicidal 4‐pyridone‐3‐carboxanilide derivatives II. Substituent effects of anilide and pyridone moieties
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机译：Quantitative structure—activity relationships of light‐dependent herbicidal 4‐pyridone‐3‐carboxanilide derivatives II. Substituent effects of anilide and pyridone moieties
AbstractThe variations in the light‐dependent herbicidal activity againstEchinochloa oryzicola of a number of 4‐pyridone‐3‐carboxanilides with various substituents on the anilide and pyridone rings have been examined by use of physicochemical substituent parameters and regression analysis.The effects of substituents of the anilide ring were such that the activity was related parabolically not only with the substituent hydrophobicity (π) but also with the steric bulk parameter (Es) of the bulkierorthosubstituent. The effect of substituents at the 1‐position of the pyridone ring was analysed with steric(STERIMOL L and B5) and electronic(γ1) parameters. That of substituents at the 5‐position of the pyridone ring was explained by a parabolic function of a steric (MR) parameter. Analyses of the activity of 105 analogs confirmed that our previous selection of a candidate compound in this series for field trials was indeed appropriate in terms of physicochemical substi
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