Connatal tuberculosis in an extremely low birth weight infant: case report and management of exposure to tuberculosis in a neonatal intensive care unit.

Saitoh M; Ichiba H; Fujioka HShintaku HYamano T

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Connatal tuberculosis in an extremely low birth weight infant: case report and management of exposure to tuberculosis in a neonatal intensive care unit.

机译：Connatal tuberculosis in an extremely low birth weight infant: case report and management of exposure to tuberculosis in a neonatal intensive care unit.

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A case of connatal tuberculosis in an extremely low birth weight infant is reported. The patient was a female with a birth weight of 973 g born in the 27th week of pregnancy. She developed respiratory distress and signs of infection immediately after birth, which did not respond to mechanical ventilation, antibiotics, and corticosteroid therapy. Connatal tuberculosis was confirmed at 48 days of age by isolation of Mycobacterium tuberculosis from the infant's tracheal aspirate and the mother's menstrual discharge. The infant died of respiratory failure at 90 days of age. Mantoux tuberculin skin tests (TST) were performed on 99 infants, 144 medical staff members, and two family members. TST conversion occurred in three medical staff members, and preventive therapy with isoniazid was initiated. Eight exposed infants had normal chest X-rays and negative gastric aspirates for acid-fast bacilli and all received preventive isoniazid therapy. No case of tuberculosis developed during the 2-year follow-up period. CONCLUSION: Connatal tuberculosis should be considered in neonatal respiratory infection resistant to antibiotics. Prevention of transmission of tuberculosis on the neonatal intensive care unit by chemoprophylaxis is important.

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来源
《European journal of pediatrics》 |2001年第2期|88-90|共3页
作者
Saitoh M; Ichiba H; Fujioka HShintaku HYamano T;
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作者单位

Department of Paediatrics, Osaka City University, Graduate School of Medicine, Japan.;

ine.yuntech.edu.tw;

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原文格式 PDF
正文语种英语
中图分类儿科学;
关键词
Infant; Very Low Birth Weight; Infection Control; Intensive Care Units; Neonatal; 婴儿; 极低出生体重; 感染控制; 加强医疗病房; 新生儿; 结核;

Connatal tuberculosis in an extremely low birth weight infant: case report and management of exposure to tuberculosis in a neonatal intensive care unit.

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