The influence of neuronal electrical activity on the mammalian central clock metabolome

Buijink M. Renate; van Weeghel Michel; Gulersonmez M. CanHarms Amy C.Rohling Jos H. T.Meijer Johanna H.Hankemeier ThomasMichel Stephan

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The influence of neuronal electrical activity on the mammalian central clock metabolome

机译：The influence of neuronal electrical activity on the mammalian central clock metabolome

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Introduction Most organisms display circadian rhythms in physiology and behaviour. In mammals, these rhythms are orchestrated by the suprachiasmatic nucleus (SCN). Recently, several metabolites have emerged as important regulators of circadian timekeeping. Metabolomics approaches have aided in identifying some key metabolites in circadian processes in peripheral tissue, but methods to routinely measure metabolites in small brain areas are currently lacking.

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《Metabolomics :》 |2018年第10期|122-122|共11页
作者
Buijink M. Renate; van Weeghel Michel; Gulersonmez M. CanHarms Amy C.Rohling Jos H. T.Meijer Johanna H.Hankemeier ThomasMichel Stephan;
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作者单位

Leiden Univ, Dept Cellular & Chem Biol, Med Ctr, Einthovenweg 20, NL-2333 ZC Leiden, Netherlands;

Leiden Univ, Div Syst Biomed & Pharmacol, LACDR, Analyt BioSci & Metabol, Einsteinweg 55, NL-2333;

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正文语种英语
中图分类生理学;
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Circadian clock metabolites; Suprachiasmatic nucleus; Neuronal activity; Small brain samples; ZIC-cHILIC-MS;

The influence of neuronal electrical activity on the mammalian central clock metabolome

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