Metabolic fingerprints of human primary endothelial and fibroblast cells

Polona Zigon; Katjusa Mrak-Poljsak; Katja LakotaMatic TerceljSasa CucnikMatija TomsicSnezna Sodin-Semrl

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Metabolic fingerprints of human primary endothelial and fibroblast cells

机译：Metabolic fingerprints of human primary endothelial and fibroblast cells

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Introduction Human primary cells originating from different locations within the body could differ greatly in their metabolic phenotypes, influencing both how they act during physiological/pathological processes and how susceptible/resistant they are to a variety of disease risk factors. A novel way to monitor cellular metabolism is through cell energetics assays, so we explored this approach with human primary cell types, as models of sclerotic disorders. Objectives In order to better understand pathophysiolog-ical processes at the cellular level, our goals were to measure metabolic pathway activities of endothelial cells and fibroblasts, and determine their metabolic phenotype profiles.

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来源
《Metabolomics :》 |2016年第5期|art. no. 92-art. no. 92|共1页
作者
Polona Zigon; Katjusa Mrak-Poljsak; Katja LakotaMatic TerceljSasa CucnikMatija TomsicSnezna Sodin-Semrl;
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作者单位

Department of Rheumatology, University Medical Centre Ljubljana, Vodnikova 62, 1000 Ljubljana;

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正文语种英语
中图分类生理学;
关键词
Cellular metabolism; Phenomics; Phenotype MicroArrays; OmniLog; Human primary cells;

Metabolic fingerprints of human primary endothelial and fibroblast cells

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