Current concepts in the management of small cell lung cancer

GantiA.K.; WestW.W.; ZhenW.

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Current concepts in the management of small cell lung cancer

机译：Current concepts in the management of small cell lung cancer

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Small cell lung cancer (SCLC) has a clinical course that is distinct from its more common counterpart non-small cell lung cancer. SCLC continues to be a major clinical problem, with an aggressive clinical course and short disease-free duration after initial therapy. Current optimal treatment consists of chemotherapy with platinum-etoposide, given concurrently with thoracic irradiation in patients with limited stage disease and chemotherapy alone in those with extensive stage. Prophylactic cranial irradiation (PCI) is recommended for patients who have responded to initial therapy, as it not only decreases the risk of brain metastases and but also improves overall survival. Newer targeted agents are currently being evaluated for this disease.

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来源
《The Indian journal of medical research.》 |2013年第6期|1043-1051|共9页
作者
GantiA.K.; WestW.W.; ZhenW.;
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作者单位

Section of Hematology-Oncology, Department of Medicine, VA Nebraska Western Iowa Health Care System;

Department of Pathology-Microbiology, University of Nebraska Medical Center, Omaha, NE, United;

Department of Radiation Oncology, University of Nebraska Medical Center, Omaha, NE, United States;

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原文格式 PDF
正文语种英语
中图分类医药、卫生;
关键词
Cisplatin; Etoposide; Prophylactic cranial irradiation; Small cell lung cancer; Thoracic radiation;

Current concepts in the management of small cell lung cancer

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