The acute lethality and endocrine effect of 1,2,3,7,8-PeCDD in juvenile goldfish(Carassius auratus)in vivo

YANG Yongbin; LIU Zhengtao; ZHENG Minghui

首页> 外文期刊>Journal of environmental sciences >The acute lethality and endocrine effect of 1,2,3,7,8-PeCDD in juvenile goldfish(Carassius auratus)in vivo

【24h】

The acute lethality and endocrine effect of 1,2,3,7,8-PeCDD in juvenile goldfish(Carassius auratus)in vivo

机译：The acute lethality and endocrine effect of 1,2,3,7,8-PeCDD in juvenile goldfish(Carassius auratus)in vivo

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相关主题

摘要

1,2,3,7,8-PeCDD was administrated to juvenile goldfish {Carassius auratus)by peritoneal injections to explore the acute lethality and endocrine effects of 1,2,3,7,8-PeCDD in vivo.The value of acute median lethal dosage(LD50)of 1,2,3,7,8-PeCDD was determined in acute lethality tests.The endocrine effect of 1,2,3,7,8-PeCDD,whose exposed concentrations were determined based on the LD50(1.84 mg/kg),was studied by measuring the plasma vitellogenin(Vtg)content in juvenile male goldfish with enzyme-linked immunosorbent assays(ELISA).Due to its significant induction of the plasma Vtg after one week's exposure in vivo in the 1/2 LD_(50)and LD_(30)groups,1,2,3,7,8-PeCDD might be one of the important contributors to the estrogenic effect of PCDDs in the environment.The values of 1/2 LD50 and LD30 were within the range of the effective dosages of 1,2,3,7,8-PeCDD,indicating that there was a certain relationship between the estrogenic effective dosages and the LD_(50).

著录项

来源
《Journal of environmental sciences》 |2008年第2期|240-245|共6页
作者
YANG Yongbin; LIU Zhengtao; ZHENG Minghui;
展开▼
作者单位

State Key Laboratory of Environmental Chemistry and Ecotoxicology,Research Center for Eco-Environmental Sciences,Chinese Academy of Sciences,Beijing 100085,China.;

China Research Academy of Environmental Sciences,Beijing 100012,China;

Health Science Center,Hebei University,Baoding 071000,China;

展开▼
收录信息美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《化学文摘》(CA);
原文格式 PDF
正文语种英语
中图分类环境与环境系统;
关键词
1; 2; 3; 7; 8-PeCDD; goldfish; endocrine effect; vitellogenin(Vtg); acute lethality; ELISA;

The acute lethality and endocrine effect of 1,2,3,7,8-PeCDD in juvenile goldfish(Carassius auratus)in vivo

摘要

著录项

相关主题

期刊订阅