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Lupus vulgaris : Unusual presentation on face

机译:寻常型狼疮:脸上异常的表现

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Lupus vulgaris is a variant of cutaneous tuberculosis. As the disease has potential to mutilate when left untreated, leaving deforming scars and dis?gurement, an early diagnosis is of paramount importance. Though the common type is plaque type, rarely mutilating and vegetative forms also are found. A 28 year old female, labourer presented with progressive annular plaque over right side of cheek extending upto right lower lid and ala of nose. There were two satellite plaques near the right side of giant lesion. On diascopy apple jelly nodule was seen. There was no regional lymhadenopathy. Histopathological examination showed many granulomas in upper dermis extending to deep dermis comprising of epitheloid cells with langhans' type of giant cells, lymphocytic infiltration & focal necrosis suggestive of lupus vulgaris. The consequences of failing to make an early diagnosis can be disastrous for the patients, as the progression of the disease can lead to necrosis, destruction of bones and cartilage leading to permanent deformity. Thus it is vital for clinicians to have a high index of suspicion of such atypical forms and take biopsy samples for histological and bacteriological studies.
机译:寻常型狼疮是皮肤结核的一种变体。由于这种疾病如果不加以治疗可能会致残,留下变形的疤痕和变形,因此早期诊断至关重要。尽管常见的类型是菌斑类型,但也很少发现具破坏性和营养性的形式。一名28岁的女工,在脸颊右侧呈现渐进环形斑块,延伸至右下眼睑和鼻翼。大病变右侧附近有两个卫星斑块。透支镜检查发现苹果果冻结节。没有局部淋巴结肿大。组织病理学检查显示,上层真皮中有许多肉芽肿,延伸至深层真皮,由上皮细胞组成,伴有朗氏型巨细胞,淋巴细胞浸润和局灶性坏死,提示寻常性狼疮。未能进行早期诊断的后果对于患者而言可能是灾难性的,因为疾病的进展会导致坏死,骨头和软骨的破坏,从而导致永久性畸形。因此,对于临床医生而言,高度怀疑此类非典型形式并采集活检样本用于组织学和细菌学研究至关重要。

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