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Miniaturized H-1-NMR method for analyzing limited-quantity samples applied to a mouse model of Leigh disease

机译：Miniaturized H-1-NMR method for analyzing limited-quantity samples applied to a mouse model of Leigh disease

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摘要

The analysis of limited-quantity samples remains a challenge associated with mouse models, especially for multi-platform metabolomics studies. Although inherently insensitive, the highly specific characteristics of nuclear magnetic resonance (NMR) spectroscopy make it an advantageous platform for global metabolite profiling, particularly in mitochondrial disease research.

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