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首页> 外文期刊>american journal of hematology >Lymphoblastic transformation of chronic myelomonocytic leukemia in an infant
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Lymphoblastic transformation of chronic myelomonocytic leukemia in an infant

机译：Lymphoblastic transformation of chronic myelomonocytic leukemia in an infant

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AbstractA 10‐month‐old infant with chronic myelomonocytic leukemia (CMML) of 5 months' duration, who had been treated only with transfusion, displayed leukemic transformation characterized by lymphoid morphology, PAS positivity, and myeloperoxidase negativity. Surface marker analysis of blast cells revealed expression of lymphoid‐associated antigens (CD10 and CD19) but not myeloid‐associated antigens (CD13, CD14, and CD33). These findings suggest that some cases of infantile CMML are clonal disorders arising in a pluripotent stem cell that can also differentiate along the lymphoid cell lineage. © 1996 Wiley

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