Alarming and Threatening Signals from Health Centers About Multi Drug Resistance Staphylococcus haemolyticus

Abbas Maleki; Sobhan Ghafourian; Morovat TaherikalaniSetareh Soroush

首页> 外文期刊>Infectious disorders drug targets >Alarming and Threatening Signals from Health Centers About Multi Drug Resistance Staphylococcus haemolyticus

【24h】

Alarming and Threatening Signals from Health Centers About Multi Drug Resistance Staphylococcus haemolyticus

机译：Alarming and Threatening Signals from Health Centers About Multi Drug Resistance Staphylococcus haemolyticus

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相关主题

摘要

Objectives: Nowadays, due to the biofilm formation among coagulase-negative staphylococci(CoNS), acquisition of antibiotic resistance and virulence genes could be noted. These organismsresemble other staphylococcus that harbor mecA gene, which encode methicillin resistancebut the diversity in CoNS is higher than other species. Based on increasing antibiotic resistancein Staphylococcus haemolyticus, analyzing of phenotypic and genotypic biofilm formation,antibiotic resistance and genes involved in this process, SCCmec and ACME typing were the aimsof the current study.Methods: 256 clinical CoNS isolates were collected that 49 isolates were identified as S.haemolyticus. For evaluation the antibiotic resistance patterns, disk agar diffusion method was applied,and also biofilm assay carried out among methicillin resistant S. haemolyticus and SCCmecand ACME typing.Results: The results of antibiotic susceptibility indicated that the highest resistance was found forcotrimoxazole and erythromycin (86.6) and the frequency of blaA (96.5) and msrA (79.3)genes was much higher than others. Among MRSH isolates 58.6 showed a weak biofilm phenotypeand 41.4 demonstrated a moderate biofilm density. Also, among the biofilm correlatedgenes, IS 256 (79.31) was the most frequent. The SCCmec typing of MRSH isolates indicatedthat the type V was dominant.Conclusion: Our findings indicated that the correlation between high rates of existence Is 256gene and high prevalence of weak biofilm phenotype was among MRSH isolates. The currentstudy revealed that multiple antibiotic resistance existed in S. haemolyticus isolates that is a warningfor public health.

著录项

来源
《Infectious disorders drug targets》 |2019年第2期|118-127|共10页
作者
Abbas Maleki; Sobhan Ghafourian; Morovat TaherikalaniSetareh Soroush;
展开▼
作者单位

Clinical Microbiology Research Center, Ilam University of Medical Sciences, Ilam, Iran;

Department of Medical Microbiology, Lorestan University of Medical Sciences, Lorestan, Iran;

展开▼
收录信息
原文格式 PDF
正文语种英语
中图分类药学;
关键词
Staphylococcus haemolyticus; biofim; SCCmec typing; CoNS; antibiotic resistance; MRSH;

Alarming and Threatening Signals from Health Centers About Multi Drug Resistance Staphylococcus haemolyticus

摘要

著录项

相关主题

期刊订阅