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Degeneration of possible serotonergic nerves in the myenteric plexus ofMytilusinduced by 5,7-dihydroxytryptamine (5,7-DHT)

机译:Degeneration of possible serotonergic nerves in the myenteric plexus ofMytilusinduced by 5,7-dihydroxytryptamine (5,7-DHT)

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Initial observations on the effects of 5,7-DHT on the myenteric plexus ofMytilusreveal extensive lesioning of monoamine nerves containing dense-cored vesicles. At least, two types of monoaminergic nerves could be recognized among the degenerating axons. The most affected were profiles with a predominance of large granular vesicles (56–200 nm) which resemble possible indoleamine nerves in the lamprey gut. The other type had small granular vesicles (40–56 nm) resembling catecholamine nerves of vertebrates. These two types of nerves possibly represent serotonergic and dopaminergic nerves, in accordance with pharmacological, biochemical and physiological evidence available in molluscs. There were, however, nerves with a population of medium-sized granular vesicles (56–130 nm) which were also da

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