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>Myosin content and vasoconstrictive ability of the proximal and distal (renin-positive) segments of the preglomerular arteriole
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Myosin content and vasoconstrictive ability of the proximal and distal (renin-positive) segments of the preglomerular arteriole
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机译:Myosin content and vasoconstrictive ability of the proximal and distal (renin-positive) segments of the preglomerular arteriole
The PAP-technique and antibodies to myosin were used to demonstrate the prerequisites for vasoconstriction in the juxtaglomerular part of the preglomerular arteriole as compared with its proximal segment in rats and mice. In contrast with the myosin-positive/renin-negative proximal part of the afferent arteriole no myosin-like activity could be demonstrated in its distal, renin-positive part. In accordance, no thick myofilaments were found in fully differentiated juxtaglomerular epithelioid cells replete with mature secretory granules. Stimulation of the renin-angiotensin system was followed by an increase of the reninpositive/myosin-negative portions of the preglomerular arteriole. Marked interspecies and internephron variations in the length of this vessel segment under control and stimulated conditions were observed.
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