Plasma ampicillin concentrations were determined in an eight#x2010;ways crossover trial involving six ruminant calves, which were treated intravenously (i.v.) with sodium ampicillin at 15.5 mg/kg and intramuscularly (i.m.) with five different ampicillin trihydrate or ampicillin anhydrate formulations at 7.7 mg/kg. The mean plasma concentration#x2010;time curve (Cp)after intravenous ampicillin sodium administration was described biexponentially, as: Cp= 38.8 e #x2010;0.0268t + 0.45 e #x2010;0.0058t.
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