Comparative evaluation of three rapid marine toxicity tests: Sea urchin early embryo growth test, sea urchin sperm cell toxicity test and microtox

Diane Nacci; Eugene Jackim; Raymond Walsh

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Comparative evaluation of three rapid marine toxicity tests: Sea urchin early embryo growth test, sea urchin sperm cell toxicity test and microtox

机译：Comparative evaluation of three rapid marine toxicity tests: Sea urchin early embryo growth test, sea urchin sperm cell toxicity test and microtox

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AbstractThree rapid marine toxicity tests were evaluated to determine their potential usefulness in a toxicity testing program: early embryo growth test and sperm cell toxicity test, both using the sea urchinArbacia punctulata, and Microtox. Toxicity values (EC50s) were derived for eight organic chemicals and five metals using each system. Results were compared with LC50 values for the same chemicals from standard aquatic tests withPimephales romelasandDaphnia magnaand for the metals withMenidia menidiaandMysidopsis bahia.The EC50 values for the sea urchin early embryo growth test for organics and the LC50 values for fish and crustaceans for organics and metals with which the rapid tests were compared were from the literature.For organic chemicals, EC50s from rapid tests closely approximated LC50s and toxicity rankings, except that the sperm cell test was particularly sensitive to 2,4‐pentanedione and 2‐methyl‐2,4‐pentanediol. EC50s for metals were generally comparable with each other and with other tests using embryo and sperm of other sea urchins and oysters but not with LC50s forMysidopsisandMenidia.These results indicate the potential value of rapid tests to screen and rank substances for toxicity. Additional information on the usefulness of these tests will be gained through continuing comparisons using a broad spectrum of single substances and complex mixtures with varying modes of

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《environmental toxicology and chemistry》 |1986年第6期|521-525|共页
作者
Diane Nacci; Eugene Jackim; Raymond Walsh;
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收录信息美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
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正文语种英语
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Rapid aquatic toxicity tests; Sperm cell test; Early embryo growth test; Microtox; Acute toxicity; Marine toxicity tests;

Comparative evaluation of three rapid marine toxicity tests: Sea urchin early embryo growth test, sea urchin sperm cell toxicity test and microtox

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