Fatal exacerbation of paraneoplastic systemic sclerosis after neoadjuvant chemotherapy in a breast cancer patient.

Kochhar R; Umbreit JN

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Fatal exacerbation of paraneoplastic systemic sclerosis after neoadjuvant chemotherapy in a breast cancer patient.

机译：Fatal exacerbation of paraneoplastic systemic sclerosis after neoadjuvant chemotherapy in a breast cancer patient.

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Paraneoplastic systemic sclerosis (SSc) occurs in about 3-7 of individuals with SSc. There are reports of accelerated SSc syndromes associated in particular with breast cancer. Further exacerbations of the rheumatic condition may be induced by treatment of the cancer. We report a 30-year-old African-American woman with a contiguous diagnosis of breast cancer and paraneoplastic SSc. She was treated with neoadjuvant chemotherapy and developed an accelerated SSc syndrome with pericarditis and cardiac tamponade, with lethal results. This case report stresses the need for control of the rheumatic condition prior to the initiation of antineoplastic therapy.

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来源
《Clinical rheumatology》 |2004年第3期|269-271|共3页
作者
Kochhar R; Umbreit JN;
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作者单位

Winship Cancer Institute, Emory University School of Medicine, PO Box 55440, Atlanta, GA 30308, USA. Ruby_Kochhar@emory.org;

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原文格式 PDF
正文语种英语
中图分类自身免疫性疾病、结缔组织疾病;
关键词
Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Paraneoplastic Syndromes; 抗肿瘤药; 乳腺肿瘤; 环磷酰胺; 阿霉素; 类肿瘤综合征; 硬皮病; 系统性;

Fatal exacerbation of paraneoplastic systemic sclerosis after neoadjuvant chemotherapy in a breast cancer patient.

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