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首页> 外文期刊>environmental toxicology and chemistry >Diagnosis of anticholinesterase poisoning in birds: Effects of environmental temperature and underfeeding on cholinesterase activity
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Diagnosis of anticholinesterase poisoning in birds: Effects of environmental temperature and underfeeding on cholinesterase activity

机译:Diagnosis of anticholinesterase poisoning in birds: Effects of environmental temperature and underfeeding on cholinesterase activity

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AbstractBrain cholinesterase (ChE) activity has been used extensively to monitor exposure to organophosphorus (OP) and carbamate (CB) insecticides in wild birds. A series of factorial experiments was conducted to assess the extent to which noncontaminant‐related environmental conditions might affect brain ChE activity and thereby confound the diagnosis of OP and CB intoxication. Underfeeding (restricting intake to 50 of control for 21 d or fasting for 1–3 d) or exposure to elevated temperature (36 ± 1°C for 1 d) caused only slightreductions (10–17)in brain AChE activity in adult male Japanese quail (Coturnix coturnix japonica). This degree of “reduction” in brain AChE activity is considerably less than the 50 “inhibition” criterion employed in the diagnosis of insecticide‐induced mortality, but nevertheless approaches the 20 “inhibition” level used as a conservative estimate of sublethal exposure to a known in

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