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首页> 外文期刊>american journal of primatology >Genetic structure of three populations of rhesus macaques (Macaca mulatta): Implications for genetic management
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Genetic structure of three populations of rhesus macaques (Macaca mulatta): Implications for genetic management

机译：Genetic structure of three populations of rhesus macaques (Macaca mulatta): Implications for genetic management

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AbstractOne of the prime concerns at zoos and at primate breeding facilities is to maintain genetic variability. This can be accomplished by avoiding inbreeding. It is relatively easy to assess genetic variability and the level of inbreeding by using pedigree information and genetic markers. In this study we used genetic markers controlled by 6 independent polymorphic loci (GPI,PGD,CA2,MPI,DIA1,Tf) to ascertain genetic variation in two captive and one wild population of rhesus monkeys. Two other loci ADA and NP were also examined and found to be monomorphic in the three populations. F‐statistics and contingency chi‐square analyses indicated that there was significant genetic differentiation among the populations. We also found that the mean heterozygosities were very similar in the three populations, in spite of the diverse breeding strategies. These data are important because rhesus monkeys are frequently used for biomedical research; and the genetic markers provide useful information for genetic management of captive colonies of nonhuman primates. © 1992 Wiley‐Lis

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