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首页> 外文期刊>annals of human genetics >Haplotype comparison in fresh mutation cases of adenomatous polyposis coli due to deletionAAAGAat codon 1309
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Haplotype comparison in fresh mutation cases of adenomatous polyposis coli due to deletionAAAGAat codon 1309

机译:Haplotype comparison in fresh mutation cases of adenomatous polyposis coli due to deletionAAAGAat codon 1309

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SummaryTo determine whether the common 5 base pair deletion (δAAAGA) at codon 1309 of theAPCgene occurs preferentially on a particular haplotype background, three intragenic polymorphisms were typed using the polymerase chain reaction in ten patients with this deletion as the disease‐causing mutation. Each case was due to fresh mutation. The data obtained provide no evidence in support of a preferential haplotype predisposing to this mutati

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