SummaryA patient with spontaneous venous thrombotic events, myocardial infarction and a positive family history of thrombosis was investigated for underlying disorders of haemostasis. Abnormally high levels of histidine‐rich glycoprotein were found. No other abnormality known or suspected of increasing the risk for thrombosis was present.Elevated levels of histidine‐rich glycoprotein appeared to be present in four other members of the family over two generations suggesting a hereditary disorder. Further study on the relation of elevated histidine‐rich glycoprotein levels and thrombosis is indi
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