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首页> 外文期刊>american journal of human biology >Prevalence of hepatitis B virus markers in several institutions for the mentally handicapped in the autonomous community of Madrid
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Prevalence of hepatitis B virus markers in several institutions for the mentally handicapped in the autonomous community of Madrid

机译:Prevalence of hepatitis B virus markers in several institutions for the mentally handicapped in the autonomous community of Madrid

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AbstractIn order to determine the prevalence of hepatitis B virus (HBV) markers, 400 patients were studied: 134 residents of an institution (RI) for the mentally retarded and 266 under non‐residential care (NRC). In the residential institutions, all markers were absent in 69 (65.7) of 105 patients with Down syndrome and 20 (69.0) of 29 clients without Down syndrome. In the NRC clients, 167 (85.6) of 195 patients with Down syndrome and 65 (91.5) of 71 clients with other mental defects (psychologically and physically handicapped, autism) had negative tests for HBV markers. The prevalence of the hepatitis B surface antigen (HBsAg) was higher in institutionalized mentally retarded (RI) and older patients (21+ years). Examination of 195 Down patients revealed a higher frequency (1.4 times) of surface antigen carriers as strictly matched non‐Down syndrome cases (point prevalences 14.2 and 10.3, respectively). The higher prevalence in affected cases appears to be primarily associated with a longer persistence of antigenemia. Results related to the sex of the patients were less clear. Neither affected nor non‐affected patients showed significant differences in prevalence among males and females. © 1995 Wiley‐L

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