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首页> 外文期刊>international journal of immunogenetics >A NEW PkPHENOTYPE IN THE P BLOOD GROUP SYSTEM
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A NEW PkPHENOTYPE IN THE P BLOOD GROUP SYSTEM

机译:A NEW PkPHENOTYPE IN THE P BLOOD GROUP SYSTEM

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SummaryA healthy 22‐year‐old woman was noted to have erythrocytes of the Pkphenotype: a strong Pkantigen, no detectable P antigen and anti‐P antibody in her serum. Her erythrocytes contained four to six times as much Pkglycolipid (globotriaosylceramide or CTH) and approximately half as much P glycolipid (globotertraosylceramide or globoside) as normal red cells. The structures of CTH and globoside were characterized by analysis of permethylated sugars and complement fixation in addition to chromaographic mobility and sugar composition. Inasmuch as the erythrocytes of two Pkindividuals that were analysed previously (Marcuset al., 1976) contained no detectable globoside, these abnormalities appear o represent a new phenotype in the P blood group s

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