AbstractStimulation of quiescent cultures of AKR‐2B cells with transforming growth factor type β (TGFβ) resulted in a transitory increase in actin cytoplasmic poly(A) + RNA. Levels of actin mRNA peaked approximately 4–8 hours subsequent to TGFβ addition and approached basal levels by 24 hours. The accumulation of actin transcripts was dose dependent and insensitive to inhibitors of protein synthesis; 1–3 ng/ml TGFβ induced maximal actin gene expression. Actin isotype‐specific probes demonstrated that both β‐ and γ‐cytoplasmic actins ar
展开▼