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Striated fibers in trichomonads: Costa proteins represent a new class of proteins forming striated roots

机译:Striated fibers in trichomonads: Costa proteins represent a new class of proteins forming striated roots

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AbstractThe production of monoclonal antibodies and the use of biochemical techniques revealed that B‐type costa proteins in trichomonads are composed of several major polypeptides with molecular weight detected between 100 and 135 kDa similar to those found in the A‐type costae. Although differences were observed between the two types in their fine structure, we tested whether proteins composing the two costa types belong to the same protein family. A polyclonal antibody produced against the 118 kDa costa protein ofTrichomonas vaginalisalso recognized a 118 kDa costa protein in all other trichomonad genera studied so far whether they have A‐ or B‐type costae. Moreover biochemical characteristics of costa proteins indicated that these proteins might represent a novel class of striated root‐forming proteins in addition to centrin, giardin, and assemblin. © 1994 Wiley

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