• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>clinical drug investigation >Economic Evaluation of a Recombinant Follicle-Stimulating Hormone (Follitropin Beta, Puregonreg;) in Infertile Women Undergoing In Vitro Fertilisation in Greece
【24h】

Economic Evaluation of a Recombinant Follicle-Stimulating Hormone (Follitropin Beta, Puregonreg;) in Infertile Women Undergoing In Vitro Fertilisation in Greece

机译：Economic Evaluation of a Recombinant Follicle-Stimulating Hormone (Follitropin Beta, Puregonreg;) in Infertile Women Undergoing In Vitro Fertilisation in Greece

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相关主题

摘要

Objective: The objective of this study was to estimate the cost effectiveness of follitropin beta (Puregonreg;; NV Organon) and urofollitropin (Metrodin HPreg;; Ares-Serono) in women undergoingin vitrofertilisation (IVF) treatment in Greece.DesignA Markov model was designed using clinical data from a large meta-analysis of IVF treatment and expert opinion on IVF patterns in Greece. The model was based on women going through the process for a maximum of three stimulation cycles. The study was conducted from a societal perspective and resource utilisation direct medical costs in 1999 Greek Drachmae (Dr), $US1 = Dr310 was quantified retrospectively using information gained from the clinical trials and expert opinion. The overall treatment costs, cost effectiveness and incremental cost effectiveness of the two treatments were determined. Sensitivity analysis was performed on critical variables.ResultsTotal direct costs per woman undergoing IVF treatment were higher for follitropin beta than urofollitropin Dr2thinsp;070 359vsDr1thinsp;711 410 ($US6679vs$US5734), reflecting the higher acquisition cost of the former. However, the cost per ongoing pregnancy for follitropin beta was lower than that for urofollitropin Dr3thinsp;373 536vsDr3thinsp;585 812 ($US10thinsp;882vs$US11thinsp;567). The additional cost for one extra ongoing pregnancy with follitropin beta in comparison with urofollitropin was Dr2thinsp;630 948 ($US8487). Sensitivity analysis showed that these results were robust to variations in critical parameters.ConclusionsIn women undergoing IVF treatment, follitropin beta is more cost effective than urofollitropin in the Greek healthcare setting.

著录项

获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号