Irritant skin reactions were produced within 1 h after application of the exocarp of sweet oranges or alchoholic extracts therefrom. Such reactions faded within 48 h. The exocarp. or extracts thereof, induced phototoxic reactions which were strongest at 72 h after exposure. The phototoxic reactions were only induced in natural blondes and only with some oranges.Thein vivophototoxic reactions were confirmedin vitro, causing a slight but clear photo‐inhibition of Candida albicans. Only some oranges inhibited growt
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