The clinical course of a patient with endometrial carcinoma in a uterus didelphys is described. The diagnosis of this rare combination can be missed unless the finding of a longitudinal vaginal septum alerts the gynecologist to make a careful search for a second cervix so that both endometrial cavities may be curetted. Preoperative external radiation is the procedure of choice to avoid the potential hazards of intracavitary radiation which may result from thinness of the myometrial wall and the asymmetry of the application.
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