Membrane Cholesterol Regulates Macrophage Plasticity in Cancer

Sica Antonio; Antonio Sica; Bleve AugustoAugusto BleveGarassino Marina ChiaraMarina Chiara Garassino

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Membrane Cholesterol Regulates Macrophage Plasticity in Cancer

机译：Membrane Cholesterol Regulates Macrophage Plasticity in Cancer

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The pro-tumoral diversion of macrophages remains an unresolved paradox of tumor immunology and a conceptual gap in the understanding of tumor biology. Goossens et al. (2019) identify a new level of cross-regulation by which tumors increase the membrane cholesterol efflux of macrophages to enhance their pro-tumoral activation in response to IL-4.

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《Cell metabolism》 |2019年第6期|1238-1240|共3页
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Sica Antonio; Antonio Sica; Bleve AugustoAugusto BleveGarassino Marina ChiaraMarina Chiara Garassino;
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Department of Pharmaceutical Sciences, Universita del Piemonte Orientale "Amedeo Avogadro", via;

Univ Piemonte Orientale Amedeo Avogadro, Dept Pharmaceut Sci, Via Bovio 6, Novara, Italy;

Fdn IRCCS Ist Nazl Tumori, Med Oncol Dept 1, Thorac Oncol Unit, Milan, Italy;

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正文语种英语
中图分类内分泌腺疾病及代谢病;
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Membrane Cholesterol Regulates Macrophage Plasticity in Cancer

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