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>Dithiocarbamate analogN‐(4‐methoxybenzyl)‐N‐dithiocarboxy‐D‐glucamine reduces the retention of ingested cadmium in rats
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Dithiocarbamate analogN‐(4‐methoxybenzyl)‐N‐dithiocarboxy‐D‐glucamine reduces the retention of ingested cadmium in rats
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机译:Dithiocarbamate analogN‐(4‐methoxybenzyl)‐N‐dithiocarboxy‐D‐glucamine reduces the retention of ingested cadmium in rats
AbstractThis study was performed to evaluate the effect of oral and intraperitoneal treatment withN‐(4‐methoxybenzyl) D‐glucamine dithiocarbamate monohydrate (MeOBDCG) after a single oral administration of115mCd to 6‐week‐old rats. Oral treatment reduced the retention of115mCd in the whole body, gut, liver and kidney by 5, 3, 4 and 3 times respectively, and intraperitoneal treatment reduced the retention by 7,2.5, 16 and 4.5 times, respectively. This finding is new, since it was believed that oral dithiocarbamate treatment would increase the toxicity and absorption of ingeste
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