Abstract:Lipid peroxidation, measured by malonyldial‐dehyde (MDA) and vitamin E in red blood cells (RBC) and plasma, was investigated in 25 hemodialysis (HD) patients before and after 6 months rhEPO therapy. RBC‐MDA was significantly elevated, but plasma MDA was in the reference range. After recombinant human erythro‐poietin (rhEPO) treatment, the MDA level was significantly decreased in both compartments. Marked vitamin E deficiency was established in RBC as well as in plasma. rhEPO therapy restored vitamin E levels in both compartments. Our data suggest a possible positive rhEPO‐antioxidant effect in HD p
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