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From particles of liquid-crystalline dispersions to rigid deoxyribonucleic acid nanoconstructions

机译：From particles of liquid-crystalline dispersions to rigid deoxyribonucleic acid nanoconstructions

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摘要

Two theoretically feasible strategies to designing the deoxyribonucleic acid (DNA) nanoconstructions are outlined. The main data on the physico-chemical properties of liquid-crystalline dispersions formed by double-stranded nucleic acid (DNA and ribonucleic acid) molecules as a result of their phase exclusion from water-salt solutions are presented and the specific features of these molecules in quasinematic layers of the liquid-crystalline particles are allocated. The basic data obtained in this field have been used as the background for the creation of the DNA nanoconstructions carrying various ‘guest’ molecules (biologically active compounds or chemical substances). The unique properties of these nanoconstructions determine the possibility of manipulation with these objects, as well as the areas of their practical application.

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