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>Potassium‐induced reverse transformation of cells infected with a temperature‐sensitive transformation mutant virus
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Potassium‐induced reverse transformation of cells infected with a temperature‐sensitive transformation mutant virus
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机译：Potassium‐induced reverse transformation of cells infected with a temperature‐sensitive transformation mutant virus
AbstractHigh potassium concentrations altered the morphology and the ability to grow in soft agar in 6m2 cells, a clone of rat kidney cells infected with a temperature‐sensitive mutant of Moloney sarcoma virus. Approximately 60 of cells exhibited normal morphology in the presence of 94.8 mM potassium in isotonic medium at the temperature permissive for transformation, whereas 100 were normal at 72 mM potassium in hypertonic media. A significant reduction of growth in soft agar was also induced with these conditions. However, the synthesis ratio of virus‐specified transforming protein to marker viral protein was not altered. Na+K+‐ATPase might play a role in this reversetransformation pr
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