Impact of glucocorticoid receptor gene (NR3C1) polymorphisms in Turkish patients with metabolic syndrome

Kaya Z.; Caglayan S.; Akkiprik M.Aral C.Ozisik G.Ozata M.Ozer A.

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Impact of glucocorticoid receptor gene (NR3C1) polymorphisms in Turkish patients with metabolic syndrome

机译：Impact of glucocorticoid receptor gene (NR3C1) polymorphisms in Turkish patients with metabolic syndrome

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Background The metabolic syndrome (MetS) is characterized by a cluster of metabolic factors, including insulin resistance and type-2 diabetes, abdominal obesity, dyslipidemia, hypertension and microalbuminuria. Impaired glucocorticoid receptor (GR) activity also plays an important role in the etiology of MetS. The objective of our study is to evaluate the effects of GR gene polymorphisms (BclI, N363S, TthIII1 and ER22/23EK) in Turkish patients with MetS.

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《Journal of endocrinological investigation.》 |2016年第5期|557-566|共10页
作者
Kaya Z.; Caglayan S.; Akkiprik M.Aral C.Ozisik G.Ozata M.Ozer A.;
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作者单位

Zorlu Ctr, Mem Wellness Endocrinol & Metab, Istanbul, Turkey;

Parc 15 Endocrinol & Metab Clin, Istanbul, Turkey;

Marmara Univ, Sch Med, Dept Med Biol, Basibuyuk Mah,Maltepe Basibuyuk Yolu Sok 9-1, TR-34854Istanbul Medipol Univ, Sch Med, Dept Internal Med, Div Endocrinol & Metab, Istanbul, TurkeyNamik Kemal Univ, Fac Arts & Sci, Dept Mol Biol, Tekirdag, Turkey;

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正文语种英语
中图分类内分泌腺疾病及代谢病;
关键词
Metabolic syndrome; Glucocorticoid receptor gene; Glucocorticoid;

Impact of glucocorticoid receptor gene (NR3C1) polymorphisms in Turkish patients with metabolic syndrome

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