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Luteinizing hormone, progesterone and the morphological development of normal and superovulated corpora lutea in sheep

机译:Luteinizing hormone, progesterone and the morphological development of normal and superovulated corpora lutea in sheep

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The development of granulosa-lutein cells was studied in 27 normal and 32 superovulated ewes between days 0–4 (day 0 began with the preovulatory LH peak in normal animals and the HCG injection in superovulated ewes). The pattern of differentiation was similar in both groups. Following initial hormonal stimulation (0–12 hours after LH or HCG), granulosa cells were approximately 100 μ2and contained small, pleomorphic nuclei with large amounts of clumped chromatin. Elongate cells lining the basement membrane possessed large, heterogeneous dense bodies, and a well-developed Golgi apparatus. Mitotic figures were observed up to 6 hours prior to ovula

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