AbstractA preparative‐scale elution chromatographic column is described which will fractionate 45 g. of polymer in a single operation. The size of the column is kept to manageable dimensions by reducing the temperature differential from 50 to 10°C. along the length of the temperature‐gradient section. It appears that this change limits the range of molecular weights that are in this section of the column at any one time which leads to a more uniform distribution of a polymer along the column. The net result is that the ratio of polymer load to cubic capacity of the column as a whole can be increased about tenfold over that for the conventional analytical column. It is shown that the equation derived by Caplan is valid under a variety of conditions and that this equation supports the arguments which lead to a reduced temperature differential in the co
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