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>Studies on pesticides based on coumarin. II. Synthesis and antifungal activity of ten 2‐alkyl‐7, 8‐dihydro‐3‐hydroxynaphtho1,2‐cchromen‐6‐ones
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Studies on pesticides based on coumarin. II. Synthesis and antifungal activity of ten 2‐alkyl‐7, 8‐dihydro‐3‐hydroxynaphtho1,2‐cchromen‐6‐ones
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机译：Studies on pesticides based on coumarin. II. Synthesis and antifungal activity of ten 2‐alkyl‐7, 8‐dihydro‐3‐hydroxynaphtho1,2‐cchromen‐6‐ones
AbstractA series of 2‐alkyl‐7, 8‐dihydro‐3‐hydroxynaphtho1,2‐cchromen‐6‐ones was synthesised by the condensation of ethyl 3, 4‐dihydro‐1‐oxonaphthalene‐2‐carboxylate with substituted phenols in the presence of POCl3. The compounds were characterised and tested for their toxicity towards the mycelial growth of seven phytopathogenic fungi in culture. Drechslera oryzae, Rhizoctonia solani and Colletotrichum falcatum exhibited maximum sensitivity to these compounds whereas Macro‐phomina phaseolina, Fusarium solani, Alternaria alternata and Pythium aphanidermatum were less sensitive. 2‐Ethyl‐7, 8‐dihydro‐3‐hydroxy‐naphtho1,2‐cchromen‐6‐ones possessed greatest toxicity with EC50values ranging from 0.2 to 2.5 μg ml−1against all
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