首页>
外文期刊>Cell motility and the cytoskeleton
>Arrangement of desmin intermediate filaments in smooth muscle cells as shown by high‐resolution immunocytochemistry
【24h】
Arrangement of desmin intermediate filaments in smooth muscle cells as shown by high‐resolution immunocytochemistry
展开▼
机译：Arrangement of desmin intermediate filaments in smooth muscle cells as shown by high‐resolution immunocytochemistry
AbstractTo gain additional information about the arrangement of intermediate filaments (IF) in normal smooth muscle, fresh avian gizzard was processed for immunoelectron microscopy. The protein A‐gold immunocytochemical technique was applied for the localization of desmin antigenic sites. Desmin‐containing IFs were located in an axial bundle that partially surrounds the nucleus and were associated with numerous mitochondria near the poles of the nucleus. The bundle probably extends the length of the cell. Antibody labeling also showed concentrations of IF around and between cytoplasmic dense bodies (CDB) and also between CDB and membrane‐associated dense bodies (MADB). The relationship between the axial bundle and the nucleus and associated mitochondria suggests that the bundle may support and define the position of these organelles in the cell. A fraying or branching of the bundle may integrate the bundle into the remaining cytoskeletal network of the
展开▼
