In vivo induction of massive proliferation, directed migration, and differentiation of neural cells in the adult mammalian brain, (vol 97, pg 14686, 2000)

Fallon J; Reid S; Kinyamu ROpole IOpole RBaratta JKorc M

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In vivo induction of massive proliferation, directed migration, and differentiation of neural cells in the adult mammalian brain, (vol 97, pg 14686, 2000)

机译：In vivo induction of massive proliferation, directed migration, and differentiation of neural cells in the adult mammalian brain, (vol 97, pg 14686, 2000)

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In backcrosses between D. koepferae and D. buzzatii, the disruption of a system of species-specific complementary factors brings about hybrid male inviability. This system consists of a lethal factor, hmi-1, linked to the X chromosome of D. koepferae, and several conspecific autosomal suppressors. However, hmi-1 hybrid males can also be rescued by factors present in some strains of D. buzzatii. The present work aims to estimate the number of hmi-1 suppressors in one of these strains by means of Markov chains. The obtained results allow discarding models with one or more chromosomes having independent suppressor effect. On the other hand, models having n chromosomes that interact in groups of r, being 1 < r less than or equal to n, to produce rescue effect, provide good approximations to the observed results. The best fit to the data is obtained with four or five chromosomes with suppressor effect, interacting epistatically in groups of three to rescue the viability of hmi-1 males. References: 23

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《Proceedings of the National Academy of Sciences of the United States of America》 |2001年第14期|8157-0|共1页
作者
Fallon J; Reid S; Kinyamu ROpole IOpole RBaratta JKorc M;
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acraaj@mail2.udc.esCarvajal AR, Univ A Coruna, Fac Ciencias, Dept Biol Celular & Mol, Campus Zapateira S-N, E-15071 La Coruna, Spain;

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收录信息美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
原文格式 PDF
正文语种英语
中图分类自然科学总论;
关键词
Evolutionary history; Inviability; Simulans; Melanogaster; Populations;

In vivo induction of massive proliferation, directed migration, and differentiation of neural cells in the adult mammalian brain, (vol 97, pg 14686, 2000)

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