Hypoxia modulates innate immune factors: A review

Mishra K. P.; Ganju Lilly; Singh Shashi Bala

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Hypoxia modulates innate immune factors: A review

机译：缺氧调节先天免疫因子：综述

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Hypoxia is an important factor for transcriptional regulation of cell metabolism and the adaptation to cellular stress. It modulates the function of phagocytic cells by stimulating surface receptors such as scavenger receptors, toll like receptors and their downstream signaling cascades. In response to hypoxia, innate immune modifiers are upregulated through pathways involving the key immune response master regulator nuclear factor-kappa B leading to the modulation of inflammatory cytokines. In this review, we highlighted the effects of hypoxia on different innate immune factors and consequences thereof. (C) 2015 Elsevier B.V. All rights reserved.

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《International immunopharmacology》 |2015年第1期|共4页
作者
Mishra K. P.; Ganju Lilly; Singh Shashi Bala;
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原文格式 PDF
正文语种 eng
中图分类药理学;
关键词
Hypoxia; Innate immunity; Phagocytosis; TLRs; Nitric oxide;

机译：缺氧;先天免疫;吞噬作用;TLRs;一氧化氮;

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专利

1. Hypoxia modulates innate immune factors: A review [J] . Mishra K. P., Ganju Lilly, Singh Shashi Bala International immunopharmacology . 2015,第1期

机译：缺氧调节先天免疫因子：综述
2. Hypoxia, Hypoxia-Inducible Factor-1α, and Innate Antileishmanial Immune Responses [J] . Valentin Schatz, Patrick Neubert, Franz Rieger, Frontiers in Immunology . 2018,第1期

机译：缺氧，缺氧诱导因子-1α和先天抗leishmanial免疫反应。
3. Hypoxia and the hypoxia-regulated transcription factor HIF-1alpha regulate innate immune responses of respiratory epithelial cells [J] . Polke M., Lepper P. M., Kamyschnikow A., International journal of medical microbiology: IJMM . 2013,第Null期

机译：低氧和低氧调节的转录因子HIF-1alpha调节呼吸道上皮细胞的先天免疫反应
4. Polyanhydride nanovaccine and cyclic dinucleotide based formulations stimulate innate immunity and modulate immune response [C] . S. L. Haughney, P. Lueth, D. Wagner, Society for Biomaterials annual meeting and exposition . 2014

机译：聚酸酐纳米疫苗和环状二核苷酸制剂可刺激先天免疫力并调节免疫反应
5. Hypoxia-induced lipid changes and their effect on innate immunity. [D] . Archer Slone, Emily E. 2013

机译：低氧诱导的脂质变化及其对先天免疫的影响。
6. Hypoxia Hypoxia-Inducible Factor-1α and Innate Antileishmanial Immune Responses [O] . Valentin Schatz, Patrick Neubert, Franz Rieger, -1

机译：缺氧缺氧诱导因子-1α和先天抗leishmanial免疫反应。
7. Hypoxia-inducible factors and innate immunity in liver cancer [O] . Vincent Wai-Hin Yuen, Carmen Chak-Lui Wong 2020

机译：肝癌中缺氧诱导因素和先天免疫力

Hypoxia modulates innate immune factors: A review

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