Besides the excretion of metabolic wastes, the kidneys regulate the balance of sodium, potassium, and acid-base (15). Impairment of certain transport functions is known to play an important role in the pathogenesis of diseases such as proteinuria and hypertension. But despite decades of research, aspects of renal epithelial transport mechanisms have yet to be fully elucidated. This editorial focus will highlight recent advances in our understanding of renal epithelial transport, obtained from experimental and theoretical studies. Some of these studies were published in response to a recent Call for Papers of this journal: Molecular Mechanism of Renal Tubule Transport.
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